Labor für Diagnostik und molekulare Therapien

1450

Wenn's weh tut!

1450

Labor für Diagnostik und molekulare Therapien
Standort
Labor für Diagnostik und molekulare Therapien der Universitätsklinik für Dermatologie und Allergologie
Landeskrankenhaus Salzburg
Müllner Hauptstraße 48
A-5020 Salzburg
Gebäude D
Eingang D6
Ebene EG
+43 (0) 5 7255-24629
v.wally@salk.at
Über unsere Einrichtung

The laboratory for “Diagnostics and Molecular Therapy” (DMT/AG Wally) is committed to the development of early diagnostics and new treatment options for dermatological conditions with urgent need, like rare cancers. Our team brings together experts in molecular biology and bioinformatics with experience in DNA/RNA sequencing and data analysis, as well as standard and innovative wet lab techniques.

A/Prof. Verena Wally, PhD, MScPH (Principal Investigator)

Julia Hummel, MSc (Scientific Associate)

Caterina Barone, MSc (Bioinformatician)

Sonja Dorfer, PhD (Post-doc)

Vanessa Walch, BSc (MSc student)

Wissenschaft und Forschung

Our projects

  • Investigation of genotype / phenotype correlations and divergences in epidermolysis bullosa (EB)
  • Drug repurposing for rare cancers and fibrosis
  • Basic research to understand pathomechanisms associated with complications and secondary manifestations arising in patients with rare diseases and dermatological conditions with urgent need
  • Development of multiaspect diagnostics for EB

Our methods

  • In silico, transcriptome-based drug repurposing
  • miRNA and RNA-Seq
  • Differential methylation analysis
  • Single-cell RNA-Seq
  • Drug efficacy testing in vitro and in vivo
  • Standard wet lab techniques

3rd party Funding

  • Land Salzburg
  • Austrian Science Fund (FWF)
  • Debra Austria
  • Paracelsus Medical University (PMU)